Chris Pine's grandmother, Anne Gwynne, is known for being one of the first scream queens in Hollywood.
1. First, Mariska Hargitay, who has notably starred as Olivia Benson in Law & Order: SVU for 26 seasons, is the daughter of actors Jayne Mansfield and Mickey Hargitay.
2. Kate Burton, who is best known for playing Ellis Grey in Grey's Anatomy and Sally Langston in Scandal, is the daughter of actors Richard Burton and Sybil Christopher.
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Richard was nominated for seven Academy Awards for his work in My Cousin Rachel, The Robe, Becket, The Spy Who Came In from the Cold, Who's Afraid of Virginia Woolf?, Anne of the Thousand Days, and Equus.
Sybil was an actor but also best known for being the founder of the NYC nightclub Arthur and the founder of the New Theatre in NYC.
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Anne is considered one of the first scream queens in Hollywood. She is best known for her work in horror films like Black Friday and House of Frankenstein. She also starred in Men of Texas, Ride 'Em Cowboy, and more.
Chris' parents, Robert Pine and Gwynne Gilford, are also actors.
4. Natasha Richardson, who is probably best known for starring as Elizabeth James in The Parent Trap, was the daughter of actor Vanessa Redgrave and director Tony Richardson.
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Vanessa won an Academy Award in 1977 for Best Supporting Actress for Julia. She also has two Emmy Awards and a Tony Award. She's best known for her work in Atonement, Howards End, Mary, Queen of Scots, and more.
Tony was a director, screenwriter, and producer. He won two Academy Awards in 1964 for Best Director and Best Picture for Tom Jones.
5. Ethan Peck, who is best known for playing Spock in Star Trek: Discovery and Star Trek: Strange New Worlds, is the grandson of actor Gregory Peck.
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Gregory is best known for starring as Atticus Finch in To Kill a Mockingbird, which earned him an Academy Award for Best Actor in 1962. He also starred in Roman Holiday, Spellbound, and more.
6. Sean Astin, who is best known for The Goonies, Rudy, The Lord of the Rings trilogy, and more, is the son of actors Patty Duke and John Astin.
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Patty won an Academy Award for Best Supporting Actress for her work in The Miracle Worker, a role she also originated on Broadway. She also starred in The Patty Duke Show, Valley of the Dolls, and more.
John, who adopted Sean, was best known for starring as Gomez Addams in The Addams Family TV series, as well as Freaky Friday, National Lampoon's European Vacation, and more.
7. Jared Harris, who is best known for his work in Mad Men, The Crown, and Chernobyl, is the son of actor Richard Harris.
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Richard was a two-time Academy Award nominee for his work in This Sporting Life and The Field. He also starred in Gladiator. He's probably best known for playing the original Dumbledore in Harry Potter and the Sorcerer's Stone and Harry Potter and the Chamber of Secrets, with the latter being his final film role.
8. Dakota Johnson, who is best known for her work in the Fifty Shades of Grey movies, How to Be Single, Suspiria, and more, is the grandaughter of actor Tippi Hedren.
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Tippi is best known for starring in Alfred Hitchcock's The Birds and the movie Marnie.
Of course, Dakota is also the daughter of actors Melanie Griffith and Don Johnson.
9. Zoë Kravitz, who is best known for her work in Big Little Lies, Mad Max: Fury Road, High Fidelity, The Batman, and more, is the granddaughter of actor Roxie Roker.
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Roxie starred as Heken Willis on The Jeffersons for eleven seasons from 1975 to 1985.
Of course, Zoë is the daughter of Lisa Bonet and Lenny Kravitz. Roxie was Lenny's mother.
10. Miguel Ferrer, who was best known for his work in Twin Peaks, Crossing Jordan, and NCIS: Los Angeles, was the son of actors Rosemary Clooney and José Ferrer.
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Rosemary was best known for starring as Betty Haynes in White Christmas. She also notably appeared in an episode of ER in 1994 alongside her nephew George Clooney. She was also a well-known singer.
José is considered one of the most celebrated Hispanic-American actors. He notably won a Tony and Academy Award for his work as Cyrano de Bergerac in the play and film of the same name. He also starred in Joan of Arc, Moulin Rouge, and more.
11. Riley Keough, who is best known for her work in Mad Max: Fury Road, Daisy Jones & the Six, and more, is the granddaughter of musician and actor Elvis Presley.
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Alongside his legendary singing career, Elvis was also known for starring in movies like Love Me Tender, Jailhouse Rock, Blue Hawaii, Viva Las Vegas, and more.
Riley is the daughter of Lisa Marie Presley, who was also a singer.
12. Oona Chaplin, who is best known for her work as Talisa Stark in Game of Thrones, is the granddaughter of actor and filmmaker Charlie Chaplin.
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Of course, Chaplin is known for his string of movies in the silent film era, most notably The Kid, A Woman of Paris, The Gold Rush, The Circus, and more.
13. Steven R. McQueen, who is best known for playing Jeremy Gilbert in The Vampire Diaries, is the grandson of actor Steve McQueen.
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Steve was known as the "King of Cool." He earned an Academy Award nomination for his work in The Sand Pebbles. He also starred in movies like The Cincinnati Kid, Nevada Smith, The Thomas Crown Affair, The Magnificent Seven, The Great Escape, and more.
In 1974, Steve was reportedly the highest-paid movie actor in the world.
14. Sam Robards, who is best known for starring in American Beauty, A.I. Artificial Intelligence, Fandango, and more, is the son of actors Lauren Bacall and Jason Robards.
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Lauren is considered one of the greatest actors of classic Hollywood. She is best known for her work in movies like To Have and Have Not, Murder on the Orient Express, The Mirror Has Two Faces, Misery, and more. She received an honorary Academy Award in 2010.
Jason is best known for playing Bed Bradlee in All the President's Men, a role that earned him an Academy Award. He also won an Oscar for his work in Julia. Jason was also known for his work in the TV series Inherit the Wind and the Broadway play The Disenchanted.
15. Anjelica Huston, who is best known for her work in Prizzi's Honor, The Addams Family, The Witches, and more, is the daughter of actor John Huston.
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John was a director, screenwriter, and actor. He won two Academy Awards for Best Director and Best Writing, Screenplay in 1948 for The Treasure of the Sierra Madre.
Anjelica's grandfather, Walter Huston, was also an actor.
16. Tony Goldwyn, who is best known for his work in Scandal, Ghost, and more, is the son of producer Samuel Goldwyn Jr. and actor Jennifer Howard.
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Samuel is best known for producing films like Mystic Pizza, The Secret Life of Walter Mitty, and more.
Jennifer was a well-known TV actor who appeared in shows like The Twilight Zone, Alfred Hitchcock Presents, Perry Mason, and more.
Tony's grandfather was Samuel Goldwyn, who was one of the founders of the iconic film studio Metro-Goldwyn-Mayer.
17. Alia Shawkat, who is best known for her work in Arrested Development and Search Party, is the granddaughter of actor Paul Burke.
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Paul was best known for his leading roles in the TV series Naked City and 12 O'Clock High. He was nominated for two Emmy Awards for Naked City, where he played Det. Adam Flint.
18. June Lockhart, who is best known for classic films like A Christmas Carol and Meet Me in St. Louis and shows like Lassie and Lost in Space, was the daughter of actors Gene Lockhart and Kathleen Lockhart.
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Gene appeared in over 300 films during his lifetime. Notably, he received an Academy Award nomination for his work as Regis in Algiers in 1938.
Kathleen was known for her roles in movies like Sweethearts, Roughly Speaking, and Penrod's Double Trouble.
19. Sarah Sutherland, who is best known for her work as Catherine Meyer in Veep, is the granddaughter of Donald Sutherland.
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Donald was best known for his work in Kelly's Heroes, M*A*S*H, Animal House, and for his portrayal of President Snow in The Hunger Games films.
Of course, Sarah is also the daughter of actor Kiefer Sutherland.
20. Abby Elliott, who is best known for The Bear and Saturday Night Live, is the granddaughter of actor Bob Elliott.
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Bob is best known as being one-half of the comedy duo Bob and Ray. He's best known for appearing in Happy Days, Newhart, Laraine & Gilda, Saturday Night Live, and more.
Abby's father, Chris Elliott, is also known for starring in Saturday Night Live and Schitt's Creek.
Abby is the third generation of the family to be featured on SNL.
21. And finally, Drew Barrymore, who is best known for her work in E.T. the Extra-Terrestrial, Scream, Charlie's Angels, The Wedding Singer, and more, is the granddaughter of actors John Barrymore and Dolores Costello.
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John was best known for his work in silent films like Dr. Jekyll and Mr. Hyde, Sherlock Holmes, and The Sea Beast. He also starred in movies like Midnight, Dinner at Eight, and more.
Dolores was nicknamed "The Goddess of the Silent Screen" by John. She is known for her work in movies like The Sea Beast, Moby-Dick, and more.
Drew's entire family — the Drew and Barrymore families — is considered an acting dynasty, with all of her paternal great-grandparents and paternal grandparents being actors.